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. 2022 Oct 12;10(10):2015. doi: 10.3390/healthcare10102015
Authors Experimental Intervention Intervention Themes Results (Compared to
Control Group)
Results Themes Medical Outcomes Reported Medical Outcome Themes Study Design
Borosund et al. Internet-based patient-provider communication service Web-based (eHealth) Intervention group reported significantly lower symptom distress, anxiety, and depression Improved in at least one area nurse-administered IPPC alone can significantly reduce depression, decreased symptom distress, decreased anxiety Improved mental health RCT
Improved mental health Improved mental health
Improved mental health Improved mental health
Improved mental health Improved mental health
Improved mental health
Freeman et al. Telemedicine (TD) [vs live vs wait list] Web-based (eHealth) TD (and Live) reported less fatigue, cognitive dysfunction, and sleep disturbance with WL Improved sleep outcomes improvements in multiple QOL domains for breast cancer survivors compared with WL.
Less fatigue, less cognitive dysfunction, fewer sleep disturbances
Improved sleep outcomes RCT
Improved sleep outcomes Improved sleep outcomes
Improved sleep outcomes Improved sleep outcomes
Wheelock et al. SIS.NET (online questionnairre with remove NP overview and follow-up) Web-based (eHealth) patients reported more new or changed symptoms compared with standard care patients Improved in at least one area This intervention facilitated symptom reporting and may provide a means of convenient symptom assessment Provided education/answered questions RCT
Improved social support/answered questions
Galiano-Castillo et al. Internet-based, tailored exercise program Web-based (eHealth) telerehabilitation group improved significantly global health status, physical, role, cognitive functioning and arm symptoms, as well as pain severity, and pain interference, compared with the control group. Improved in at least one area Improved physical health, cognitive functioning, pain severity, and pain interference Improved physical health RCT
Improved global health/baseline function Improved sleep outcomes
Improved sleep outcomes Less pain
Less numbness/pain/swelling Improved quality of life
Improved quality of life
Admiraal et al. web-based psychoeducation for breast cancer (ENCOURAGE) Web-based (eHealth) No statistically significant differences between control and intervention for optimism or control over future Improved in at least one area For clinical distressed patients, use of the intervention increased optimism and control over future Improved mental health RCT
Improved mental health Improvements not statistically significant
No statistically significant differences
Fazzino et al. telephone (weekly) Telephone No control group. Distance-based weight loss program can be successful Improved in at least one area Moderate-to-vigorous physical activity significantly increased from baseline to 6 months. Improved physical health Non-experimental (no randomization, no control)
Improved body image Improved body image
No statistically significant differences Improvements not statistically significant
Han et al. eHealth system (Comprehensive Health Enhancement Support System, CHESS) Web-based (eHealth) No control group. cancer patients’ access to more complex tools generates more use with their time spreading out over the diverse services. Complexity of tool takes more time to process Communication functions drive long-term engagement with the system. Provided education/answered questions Pre-post
Uhm et al. mHealth mHealth Improved exercise, but not statistically different than control Improved in at least one area Improved exercise, but not statistically different than control Improved physical health Quasi-experimental
Improved exercise Improvements not statistically significant
No statistically significant differences
Kim et al. mHealth (mobile game) mHealth Improved drug adherence, lower side effects of chemotherapy (nausea, fatigue, numbness of hand or foot, and hair loss). Improved quality of life. No significant difference in depression or anxiety Improved in at least one area Improved drug adherence, lower side effects of chemotherapy (nausea, fatigue, numbness of hand or foot, and hair loss). Improved quality of life. Improved medication adherence. No significant difference in depression or anxiety Less nausea/vomiting RCT
Less nausea/vomiting Less numbness
Less numbness/pain/swelling Improved physical health
Improved physical health Improved quality of life
Improved quality of life Improved medication adherence
McCarthy et al. nurse-led telemedicine delivered, cognitive behavioral therapy Web-based (eHealth) participants reported improvements in sleep outcomes, including SE and SL. QOL and daily functioning improved, but anxiety and depression did not. Improved in at least one area participants reported improvements in sleep outcomes, including SE and SL. QOL and daily functioning improved, but anxiety and depression did not. Improved sleep outcomes Quasi-experimental
Improved sleep outcomes Improved quality of life
Improved quality of life
Visser et al. tablet online support group mHealth No statistically significant differences between control and intervention for distress and empowerment. Greater peer support identified in control. Improved in at least one area No improvement with intervention. Satisfaction very low. Provided education/answered questions RCT
Improved social support/answered questions
Zachariae et al. Internet-delivered cognitive-behavioral therapy (iCBT) Web-based (eHealth) Statistically significant improvements observed for all sleep-related outcomes (fatigue, sleep disturbances, total sleep time). Improved in at least one area Reduced insomnia, increased sleep quality, increases sleep efficiency, increased total sleep time, improved time in bed, reduced fatigue Improved sleep outcomes RCT
Improved sleep outcomes Improved sleep outcomes
Improved sleep outcomes Improved sleep outcomes
Improved sleep outcomes Improved mental health
Ariza-Garcia et al. web-based exercise system (e_CuidateChemo) Web-based (eHealth) Functional capacity improved significantly, abdominal strength, lower body strength, back strength Improved in at least one area Intervention increased exercise capacity by 10.8% (33.4% reached a normal exercise capacity compared with 12.3% in control). Functional capacity, abdominal strength, lower body strength, back strength improved significantly. Improved physical health RCT
Improved physical health Improved physical health
Improved physical health Improved physical health
Improved physical health Improved physical health
Crafoord et al. mHealth app for symptom self-management mHealth Daily symptom reporting created feelings of having continuous contact with health care professionals, being acknowledged, and safe. Improved in at least one area Engagement was very high for intervention. The app promoted patient participation in their care. long-term engagement with intervention Mixed Methods
Provided education/answered questions Provided education/answered questions
Ferrante et al. mHealth/eHealth tools mHealth + eHealth No statistically significant differences between weight lost in both groups. Waist circumference improved more, quality of life more, and use of strategies for healthy eating and decreasing calories. Improved in at least one area Effective at weight loss, but not statistically significant Improved body image RCT
Improved body image Improvements not statistically significant
Improved quality of life
No statistically significant differences
Fjell et al. mHealth app (Interaktor) during neoadjuvant chemo mHealth statistically significant less symptom prevalence in nausea, vomiting, feeling sad, appetite loss and constipation. Overall symptom distress and physical symptom distress were rated statistically significant lower in the intervention group. Further, emotional functioning was rated statistically significant higher in the intervention group. Improved in at least one area statistically significant less symptom prevalence in nausea, vomiting, feeling sad, appetite loss and constipation. Overall symptom distress and physical symptom distress were rated statistically significant lower in the intervention group. Further, emotional functioning was rated statistically significant higher in the intervention group. Less nausea/vomiting RCT
Less nausea/vomiting
Less nausea/vomiting Less nausea/vomiting
Improved mental health Improved mental health
Improved mental health Improved mental health
Improved physical health Improved physical health
Hou et al. mHealth app for self-management support (BCSMS) mHealth Mean quality of life scores and global health higher Improved in at least one area Mean quality of life scores and global health higher Improved quality of life RCT
Improved quality of life Improved physical health
Improved global health/baseline function
Lally et al. we-based, psychoeducational distress self-management program (CaringGuidance) Web-based (eHealth) post hoc analysis showed significant group differences in slopes occurring between study months 2 and 3 on distress and depressive symptoms Improved in at least one area post hoc analysis showed significant group differences in slopes occurring between study months 2 and 3 on distress and depressive symptoms Improved mental health True experiment
Improved mental health Improved mental health
Improved mental health
Lozano-Lozano et al. mHealth (BENECA) + rehab mHealth Both groups showed improved outcomes, but global QoL was significantly better with intervention. Improvement in upper-limb functionality also higher Improved in at least one area Both groups showed improved outcomes, but global QoL was significantly better with intervention. Improvement in upper-limb functionality also higher Improved quality of life RCT
Improved quality of life Improved arm symptoms/upper limb functionality
Improved arm symptoms/upper limb functionality
van der Hout et al. eHealth (Oncokompas) symptom self-management app Web-based (eHealth) Oncokompas did not improve the amount of knowledge, skills, and confidence for self-management in cancer survivors. No statistically significant differences No difference between groups Improvements not statistically significant RCT
Çınar et al. mHealth app for education, symptom tracking, and management mHealth QoL of the treatment group after intervention increased and distress level was lower Improved in at least one area QoL of the treatment group after intervention increased and distress level was lower Improved quality of life True experiment
Improved quality of life Improved mental health
Improved mental health
Fang et al. decision-support app (Pink Journey) Web-based (eHealth) body image distress declined significantly for the intervention group but increased for the control group. no significant difference in decision conflict, decision regret, anxiety, or depression. Improved in at least one area Decrease in body image, regret, anxiety, & distress Improved body image RCT
Improved body image Improved mental health
Improved mental health Improved mental health
Improved mental health Improved mental health
Improved mental health
Krzyzanowska et al. telephone based management of toxicities Telephone No differences in self-efficacy, anxiety, or depression No statistically significant differences No differences in self-efficacy, anxiety, or depression Improvements not statistically significant RCT
Kumar et al. Teleconsultation Telephone No control group. Concerns and questions answered through intervention Improved in at least one area Breast conservation surgery Provided education/answered questions Qualitative
Provided education/answered questions
Lai et al. Telemedicine (VTC) Occupational Therapy Web-based (eHealth) No control group. Patients regained baseline function within a mean of 42.4 days after surgery and after an average of three sessions Improved in at least one area all regained baseline functional status and full range of motion Improved physical health Non-experimental (no randomization, no control)
Improved global health/baseline function
Öztürk et al. mHealth symptom monitoring app mHealth Effective at decreasing nausea-vomiting, raising sexual function and sexual enjoyment Improved in at least one area Symptom monitoring with mHealth highly effective in controlling physical symptoms Less nausea/vomiting True experiment
Less nausea/vomiting Less nausea/vomiting
Less nausea/vomiting Improved quality of life
Improved quality of life Improved physical health
Improved physical health
Reeves et al. mHealth weight-loss mHealth Improved weight reduction (over control) fat mass, metabolic syndrome risk score, waist circumference, fasting plasma glucose, and quality of life Improved in at least one area Improved weight reduction (over control) fat mass, metabolic syndrome risk score, waist circumference, fasting plasma glucose, and quality of life Improved body image RCT
Improved body image Improved body image
Improved body image Improved body image
Improved body image Improved fasting plasma glucose
Improved fasting plasma glucose Improved quality of life
Improved quality of life
Wagner et al. eHealth (Fear of recurrence, FoF) telecoaching Web-based (eHealth) Significantly reduced fear of recurrence. Telecoaching improved adherence and retention. Improved in at least one area Reduced fear of recurrence. Telecoaching improved adherence and retention. Improved mental health RCT
Improved mental health long-term engagement with intervention
Improved medication adherence
Bandani-Susan et al. mHealth education mHealth Mean score of cancer fatigue decreased and body image increased significantly Improved in at least one area Decreased fatigue, increased body image Improved sleep outcomes RCT
Improved sleep outcomes Improved body image
Improved body image
Fu et al. mHealth pain-management mHealth Participants in the intervention were more likely to experience complete reduction in pain and soreness, lower median severity scores and general body pain, less arm/hand swelling, heaviness, redness, and limited movement in shoulder Improved in at least one area Less pain, less soreness, less swelling, less heaviness, less redness, less limited movement in shoulder Less pain RCT
Less numbness/pain/swelling Less pain
Less numbness/pain/swelling Less pain
Less numbness/pain/swelling Less numbness
Less numbness/pain/swelling Improved arm symptoms/upper limb functionality
Improved arm symptoms/upper limb functionality
Gao et al. mHealth Tai Chi and health education mHealth A significant time effect for mental health, physical health, but not for stress. Improved in at least one area Tai Chi participants had a significantly better mental health at follow up. Improved mental health RCT
Improved mental health Improved physical health
Improved physical health
Medina et al. eHealth ecosystem (ICOnnecta) Web-based (eHealth) Strong social support led to better psychosocial course Improved in at least one area ICOnnecta supports the development of a digital relation with healthcare services Improved mental health Quasi-experimental
Improved social support/answered questions
Improved mental health
Oswald et al. eHealth cognitive-behavioral therapy (iCBT) Web-based (eHealth) Improvements in insomnia, sleep efficiency, and sleep disturbance Improved in at least one area Improvements in insomnia, sleep efficiency, and sleep disturbance Improved sleep outcomes RCT
Improved sleep outcomes Improved sleep outcomes
Improved sleep outcomes Improved sleep outcomes
Improved sleep outcomes