TABLE 2.
Amino acid changes in P. ovale spp. orthologous proteins to major P. falciparum drug-resistance genes
| Species | Isolate | Crt | Dhfr | Dhps | Mdr | k13 |
|---|---|---|---|---|---|---|
| P. ovale curtisi | Poc1 | H98P | K189E and D275G | I1303V | ||
| Poc2 | H98P | I1303V | ||||
| Poc3 | A15S, S58R and H98P | |||||
| Poc4 | A15S | |||||
| Poc5 | ||||||
| P. ovale wallikeri | Pow1 | C19G | F34N | |||
| Pow2 | C19G | |||||
| Pow3 | C19G | |||||
| Pow4 | C19G and L216F | |||||
| Pow5 | F57L and S58R | |||||
| Pow6 | C19G and L216F | S113N |