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. 2022 Sep 13;10(5):e00726-22. doi: 10.1128/spectrum.00726-22

TABLE 2.

Amino acid changes in P. ovale spp. orthologous proteins to major P. falciparum drug-resistance genes

Species Isolate Crt Dhfr Dhps Mdr k13
P. ovale curtisi Poc1 H98P K189E and D275G I1303V
Poc2 H98P I1303V
Poc3 A15S, S58R and H98P
Poc4 A15S
Poc5
P. ovale wallikeri Pow1 C19G F34N
Pow2 C19G
Pow3 C19G
Pow4 C19G and L216F
Pow5 F57L and S58R
Pow6 C19G and L216F S113N