Table 3.
Details of antidepressants and other psychotropic drugs prescribed.
| Drug Name | No. of Patients (%) | ATC Code | PDD (mg) | DDD (mg) | PDD/DDD | Mild Depression [n = 32 (%)] | Moderate Depression [n = 103 (%)] | Moderately Severe [n = 15 (%)] | Moderately Severe with Psychotic Symptoms [n = 4 (%)] |
|---|---|---|---|---|---|---|---|---|---|
| Selective serotonin reuptake inhibitors (SSRIs) | |||||||||
| Escitalopram | 37 | N06AB10 | 16 | 10 | 1.6 | 6 (18.75) | 27 (26.21) | 3 (20) | 1 (25) |
| Sertraline | 26 | N06AB06 | 57 | 50 | 1.1 | 8 (25) | 15 (14.56) | 2 (13.33) | 1 (25) |
| Fluoxetine | 9 | N06AB03 | 9.7 | 20 | 0.5 | 1 (3.125) | 5 (4.85) | 3 (20) | 0 |
| Paroxetine | 4 | N06AB05 | 22 | 20 | 1.1 | 0 | 4 (3.88) | 0 | 0 |
| Serotonin and norepinephrine reuptake inhibitors (SNRIs) | |||||||||
| Duloxetine | 3 | N06AX21 | 33 | 60 | 0.5 | 0 | 3 (2.91) | 0 | 0 |
| Desvenlafaxine | 1 | N06AX23 | 50 | 50 | 1 | 1 (3.125) | 0 | 0 | 0 |
| Tricyclic antidepressants | |||||||||
| Amitriptyline | 33 | N06AA09 | 20 | 75 | 0.26 | 6 (18.75) | 22 (21.36) | 4 (26.67) | 0 |
| Imipramine | 1 | N06AA02 | 25 | 100 | 0.25 | 0 | 1 (0.97) | 0 | 0 |
| Serotonin and α-2 adrenergic antagonists | |||||||||
| Mirtazapine | 2 | N06AX11 | 7.5 | 30 | 0.25 | 0 | 1 (0.97) | 1 (6.67) | 0 |
| Diazepines, oxazepines, thiazepines and oxepines | |||||||||
| Quetiapine | 10 | N05AH04 | 108 | 400 | 0.27 | 2 (6.25) | 6 (5.83) | 0 | 2 (50) |
| Olanzapine | 8 | N05AH03 | 8.75 | 10 | 0.87 | 2 (6.25) | 6 (5.83) | 0 | 0 |
| Other antipsychotics | |||||||||
| Risperidone | 15 | N05AX08 | 1.63 | 5 | 0.32 | 4 (12.5) | 6 (5.83) | 0 | 0 |
| Aripiprazole | 11 | N05AX12 | 8.45 | 15 | 0.56 | 3 (9.375) | 7 (6.80) | 0 | 1 (25) |
| Lithium | 5 | N05AN01 | 482.6 | 1773.3 | 0.27 | 1 (3.125) | 3 (2.91) | 0 | 1 (25) |
| Monoamine oxidase B inhibitors | |||||||||
| Rasagiline | 1 | N04BD02 | 1 | 1 | 1 | 1 (3.125) | 0 | 0 | 0 |
| Benzodiazepine derivative | |||||||||
| Clonazepam | 31 | N03AE01 | 1.9 | 8 | 0.23 | 7 (21.875) | 20 (19.42) | 5 (33.33) | 0 |
| Clobazam | 4 | N05BA09 | 7.5 | 20 | 0.37 | 2 (6.25) | 2 (1.94) | 0 | 0 |
| Zolpidem | 1 | N05CF02 | 5 | 10 | 0.5 | 0 | 1 (0.97) | 0 | 0 |
| Anticholinergics | |||||||||
| Donepezil | 3 | N06DA02 | 5 | 7.5 | 0.66 | 2 (6.25) | 1 (0.97) | 0 | 0 |
| Benzamides | |||||||||
| Amisulpride | 5 | N05AL05 | 160 | 400 | 0.4 | 0 | 5 (4.85) | 0 | 0 |
| Fixed dose combination therapy | |||||||||
| Escitalopram + Clonazepam | 5 | Not Applicable | 1 (3.125) | 3 (2.91) | 1 (6.67) | 0 | |||
| Risperidone + Trihexyphenidyl | 4 | Not Applicable | 1 (3.125) | 1 (0.97) | 0 | 2 (50) | |||
| Desvenlafaxine + Clonazepam | 3 | Not Applicable | 0 | 1 (0.97) | 2 (13.33) | 0 | |||
| Amitryptyline + Chlordiazepoxide | 2 | Not Applicable | 0 | 2 (1.94) | 0 | 0 | |||
| Paroxetine + Clonazepam | 2 | Not Applicable | 0 | 1 (0.97) | 1 (6.67) | 0 | |||