FIG 3.
DMS3acrIF1 mitigates clinically isolated P. aeruginosa infection. The clinically isolated P. aeruginosa (5 × 108 CFU/mL) were treated with DMS3acrIF1 or control phages for 48 h (1 × 108 PFU/mL, MOI = 0.2). The growth kinetics of P. aeruginosa upon phage infection were obtained by measuring the OD600 nm at 20 min intervals up to 48 h at 37°C with constant shaking. Data were presented as mean ± standard error of the mean (SEM), determined from biological triplicates and analyzed via a one-way ANOVA compared against a control group (*, P < 0.05; **, P < 0.01; ***, P < 0.001; ****, P < 0.0001).