Figure 6.

Effects of taltirelin with and without trazodone on tongue, diaphragm, and postural (neck) motor activity and electroencephalogram power. Box (25th and 75th percentiles) and whisker (5th and 95th percentiles) plots show group data (n = 19, 10 males and 9 females, no individual symbols) from non-rapid eye movement (non-REM) sleep after intraperitoneal injections of taltirelin with or without coadministration of trazodone. Individual data in males (n = 10) and females (n = 9) are shown on the left and right, respectively, of each group plot. Data are shown for the 1st to 3rd and 3rd to 5th hours postinjection, in comparison to the 2nd to 4th hours used in the major analyses. The mean and median are shown by the thicker and thinner lines. *P < 0.05 between the indicated conditions. AU, arbitrary units; EEG, electroencephalogram; EMG, electromyogram; Tal, taltirelin; Traz, trazodone; Veh, vehicle. See text for further details.