Table 1.

Physiological parameters assessed

	Control	Meno
Age, moa	8–12	8–12
Body weight, ga	27.1 ± 0.8	28.5 ± 1.3
Systolic blood pressure, mmHga	105 ± 4.7	106.8 ± 6.6
Heart wt-to-body wt ratio, g/ga	0.006 ± 0.001	0.005 ± 0.001
Kidney wt-to-body wt ratio, g/ga	0.012 ± 0.001	0.014 ± 0.001
Ovaries wet weight, mgb	5.23 ± 0.47	2.91 ± 0.34*
Ovaries-to-body weight ratio, mg/gb	0.222 ± 0.020	0.123 ± 0.014*
Circulating estradiol, pg/mLb	5.641 ± 1.614	Undetected

Values are means ± SE; ^an = 16 mice/group; ^bn = 7 and 5 mice/group, control vs. menopause (Meno). *P < 0.05, 2-tailed Student’s t test.