TABLE 2.
Polymorphisms observed in Pfdhfr from P. falciparum isolates imported from central Africa
| Country | No. of samples | No. of isolates with SNP (%) |
No. of isolates with haplotype (%) |
||||||
|---|---|---|---|---|---|---|---|---|---|
| N51I | C59R | S108N | N51C59S108 | N51C59N108 | I51C59N108 | N51R59N108 | I51R59N108 | ||
| Cameroon | 59 | 57 (96.61) | 58 (98.31) | 58 (98.31) | 1 (1.69) | 0 | 0 (0) | 1 (1.69) | 57 (96.61) |
| Angola | 45 | 40 (88.89) | 36 (80.00) | 44 (97.78) | 1 (2.22) | 0 | 8 (17.78) | 4 (8.89) | 32 (71.11) |
| Congo DR | 42 | 41 (97.62) | 37 (88.10) | 42 (100.00) | 0 | 1 (2.38) | 4 (9.52) | 0 | 37 (88.10) |
| Equatorial Guinea | 36 | 36 (100.00) | 36 (100.00) | 36 (100.00) | 0 | 0 | 0 | 0 | 36 (100.00) |
| Gabon | 14 | 14 (100.00) | 14 (100.00) | 14 (100.00) | 0 | 0 | 0 | 0 | 14 (100.00) |
| Congo | 12 | 11 (91.67) | 11 (91.67) | 12 (100.00) | 0 | 0 | 1 (8.33) | 1 (8.33) | 10 (83.33) |
| Chad | 10 | 8 (80.00) | 10 (100.00) | 10 (100.00) | 0 | 0 | 0 (0) | 2 (22.00) | 8 (80.00) |
| Central African Republic | 4 | 4 (100.00) | 3 (75.00) | 4 (100.00) | 0 | 0 | 1 (25.00) | 0 | 3 (75.00) |
| Total | 222 | 211 (95.05) | 205 (92.34) | 220 (99.10) | 2 (0.90) | 1 (0.45) | 14 (6.31) | 8 (3.60) | 197 (88.74) |