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. 2022 Sep 19;10(5):e02005-22. doi: 10.1128/spectrum.02005-22

TABLE 2.

Polymorphisms observed in Pfdhfr from P. falciparum isolates imported from central Africa

Country No. of samples No. of isolates with SNP (%)
No. of isolates with haplotype (%)
N51I C59R S108N N51C59S108 N51C59N108 I51C59N108 N51R59N108 I51R59N108
Cameroon 59 57 (96.61) 58 (98.31) 58 (98.31) 1 (1.69) 0 0 (0) 1 (1.69) 57 (96.61)
Angola 45 40 (88.89) 36 (80.00) 44 (97.78) 1 (2.22) 0 8 (17.78) 4 (8.89) 32 (71.11)
Congo DR 42 41 (97.62) 37 (88.10) 42 (100.00) 0 1 (2.38) 4 (9.52) 0 37 (88.10)
Equatorial Guinea 36 36 (100.00) 36 (100.00) 36 (100.00) 0 0 0 0 36 (100.00)
Gabon 14 14 (100.00) 14 (100.00) 14 (100.00) 0 0 0 0 14 (100.00)
Congo 12 11 (91.67) 11 (91.67) 12 (100.00) 0 0 1 (8.33) 1 (8.33) 10 (83.33)
Chad 10 8 (80.00) 10 (100.00) 10 (100.00) 0 0 0 (0) 2 (22.00) 8 (80.00)
Central African Republic 4 4 (100.00) 3 (75.00) 4 (100.00) 0 0 1 (25.00) 0 3 (75.00)
 
Total 222 211 (95.05) 205 (92.34) 220 (99.10) 2 (0.90) 1 (0.45) 14 (6.31) 8 (3.60) 197 (88.74)