TABLE 1.

Neutrophil phagocytosis, killing, and ROI production in controls and patients with septicemia with the same underlying conditions

Test and parameter	Value (mean ± SD) for:		P value
	Control patients	Sepsis patients
Microscopic phagocytosis assays
% Phagocytosis	89 ± 5	39.8 ± 14	<0.001
Number of E. coli per neutrophil	6.4 ± 1.6	2.9 ± 0.7	<0.001
% of killed E. coli	61.1 ± 3.4	39 ± 10.5	<0.001
FACS analysis (FITCa-E. coli), fluorescence channel	441 ± 93	212 ± 61	0.002
Cytochrome c reduction assays
Basal nmol of O2−/106 neutrophils	1.7 ± 1.3	3.6 ± 1.9	0.01
Stimulated nmol of O2−/106 neutrophils	57.0 ± 13	29.3 ± 14	<0.001
FACS analysis (rhodamine fluorescence), fluorescence channel	78 ± 21	26 ± 12	<0.001

^aFITC, fluorescein isothiocyanate.