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. 2022 Oct 11;23(20):12093. doi: 10.3390/ijms232012093

Figure 3.

Figure 3

Modulation of microgliosis by E2F4DN in the cerebral cortex of 1-year-old 5xFAD mice. (a) Iba1 immunostaining in the cerebral cortex of mice of the indicated genotypes at 1 year. Numbers refer to the different cortical layers (identified by DAPI staining; not shown). Inserts show the high magnifications of the indicated dashed boxes. (b) Percentage of the area occupied by Iba1 immunostaining in the cerebral cortex of mice of the indicated genotypes at 1 year. (c) Percentages of the area occupied by Iba1 immunostaining in the indicated cortical layers at 1 year. * p < 0.05; ** p < 0.01; *** p < 0.001 (one-way ANOVA followed by post hoc Newman-Keuls test). Scale bar: 100 μm.