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Modulation of astrogliosis by E2F4DN in the hippocampus of 1-year-old 5xFAD mice. (a) GFAP immunostaining (arrow) in the hippocampus of mice with the indicated genotypes. Inserts show the high magnifications of the indicated dashed boxes. DAPI counterstaining was included to identify the hippocampus. (b) Percentage of the area occupied by GFAP immunostaining in the hippocampus. Scale bar: 100 μm.
