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. 2022 Oct 12;23(20):12123. doi: 10.3390/ijms232012123

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Identification of DEGs between the two clusters grouped by mitophagy-related gene set and functional enrichment analysis. (A) Volcano plot of DEGs between two clusters with different mitophagy-related gene expression. The red and blue points represent up- and downregulated genes with statistical significance, respectively. (B) Heatmap of the top 50 up- and downregulated genes with the most differential changes. (C,D) KEGG/GO analysis of DEGs that were upregulated in cluster 1. (E,F) KEGG/GO analysis of DEGs that were downregulated in cluster 1. DEG: differentially expressed genes.