FIG. 1.

Comparison of EGFR mutation detection with mutation-harboring oligos spiked-in saliva samples with or without Spectrum preservative solution. Saliva samples collected from four different healthy subjects with or without Spectrum preservative solution. Three EFIRM assays for L858R, T790M, and exon19 del detection were tested. The p-value was determined by two-way analysis of variance and the error bar represents the standard error in duplicates of four samples. ****Means p < 0.0001. EFIRM, electric field-induced release and measurement; EGFR, epidermal growth factor receptor.