Table 2.
Neurodevelopment association with prenatal blood lead, mercury, and manganese levels in 1–12-months-old children in Sonora, Mexico a.
| Metals (µg/L) | Bayley Scales | ||
|---|---|---|---|
| Language | Motor | Cognitive | |
| ß (CI 95%) | ß (CI 95%) | ß (CI 95%) | |
| n = 522 | |||
| Hg b | −0.51 (−1.43–0.41) | 0.04 (−0.89–0.97) | −0.25 (−1.16–0.67) |
| Pb c | −0.15 (−0.24–−0.56) ** | −0.08 (−0.17–0.01) | −0.01 (−0.10–0.08) |
| n = 252 | |||
| Pb only in women with Hg >1.9 b | −0.16 (−0.29–−0.34) ** | −0.08 (−0.20–0.04) | −0.03 (−0.15–0.09) |
| n = 247 | |||
| Pb only in women with Mn <9.6 b | −0.19 (−0.31–−0.06) ** | −0.01 (−0.02–0.02) | −0.08 (−0.02–0.04) |
| Mn b | n = 364 | ||
| 1st tertile (2.40–6.86) | −1.21 (−3.71–1.30) | −1.02 (−3.55–1.52) | 0.21 (−2.16–2.58) |
| 2nd tertile (6.87–12.80) | Ref. | Ref. | Ref. |
| 3rd tertile (12.9–21.30) | −1.95 (−4.30–0.40) | −1.20 (−3.58–1.17) | −1.25 (−3.48–0.97) |
a Associations evaluated through multilevel models based on child and municipality of origin. b Model adjusted by offspring’s sex, BMI (z—score), age, and maternal IQ. c Model adjusted by offspring’s sex, BMI (z—score), age (age + age2), and maternal IQ. ** p < 0.01.