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. 2022 Oct 12;23(20):12170. doi: 10.3390/ijms232012170

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Expression of genes related to cell death in rods (a) and cones (b). Bar plots showing transcriptomic changes in genes coding for phosphodiesterase 6 (PDE6; i.e., Pde6a, Pde6b, Pde6c, Pde6g, Pde6h), cyclic-nucleotide-gated channels (CNG channels; i.e., Cnga1, Cngb1, Cnga3, Cngb3), protein kinase G (PKG; Prkg1, Prkg2), poly(ADP−ribose) polymerase (PARP; Parp1, Parp2), histone deacetylase (HDAC; Hdac1, Hdac2, Hdac3), Na⁺/Ca²⁺ exchanger 1 (NCX1; Slc8a1), cAMP response element-binding protein 1 (Creb1) and cAMP response element modulator (Crem), and apoptosis inducing factor 1 (Aifm1). The x−axis indicates postnatal day (P), and y−axis depicts average log₂ fold change; positive values indicating higher expression in rd1 rods/cones. Bars were color−coded (red for rods; blue for cones) for p-values < 0.05.