Skip to main content
. 2022 Oct 14;23(20):12248. doi: 10.3390/ijms232012248

Table 2.

Top 25 pathways related with immune system.

Pathway Adjusted p Value
Fc epsilon receptor (FCERI) signaling 1.88 × 10−11
Signaling by the B Cell Receptor (BCR) 4.35 × 10−10
Innate Immune System 6.25 × 10−10
Downstream signaling events of B Cell Receptor (BCR) 7.55 × 10−9
Adaptive Immune System 1.82 × 10−7
TAK1 activates NFkB by phosphorylation and activation of IKKs complex 2.35 × 10−6
Toll Like Receptor 10 (TLR10) Cascade 2.51 × 10−6
Toll Like Receptor 5 (TLR5) Cascade 2.51 × 10−6
MyD88 cascade initiated on plasma membrane 2.51 × 10−6
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 2.74 × 10−6
Toll Like Receptor 7/8 (TLR7/8) Cascade 2.92 × 10−6
MyD88 dependent cascade initiated on endosome 2.92 × 10−6
MyD88:Mal cascade initiated on plasma membrane 4.24 × 10−6
Toll Like Receptor TLR1:TLR2 Cascade 4.24 × 10−6
Toll Like Receptor TLR6:TLR2 Cascade 4.24 × 10−6
Toll Like Receptor 2 (TLR2) Cascade 4.24 × 10−6
IRAK1 recruits IKK complex 4.26 × 10−6
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 4.26 × 10−6
Cytokine Signaling in Immune system 4.27 × 10−6
TRAF6 mediated NF-kB activation 5.53 × 10−6
Toll Like Receptor 9 (TLR9) Cascade 3.67 × 10−6
CLEC7A (Dectin-1) signaling 1.29 × 10−6
Interleukin-1 signaling 1.29 × 10−6
Role of LAT2/NTAL/LAB on calcium mobilization 1.81 × 10−6
DAP12 signaling 1.09 × 10−4