TABLE 3.
Demographics, comorbidities, clinical characteristics, and outcomes of hospitalized patients with MDR Pseudomonas aeruginosa infection
| Demographics | N (3,763 unique patients) |
|---|---|
| Age (yr), mean (SD) | 69.4 (12.0) |
| Male | 3,680 (97.8%) |
| White Black Asian |
2,537 (67.4%) 951 (25.3%) 19 (0.5%) |
| Hispanic | 320 (8.5%) |
| Married | 1,766 (46.9%) |
| Admission source Home/community Long-term care Another hospital Other/unknown |
3,092 (82.2%) 389 (10.3%) 161 (4.3%) 121 (3.2%) |
| Intensive care unit during current admission | 1,942 (51.6%) |
| Charlson score, Median (interquartile range) | 4 (2–6) |
| Elixhauser score, Median (interquartile range) | 5 (4–7) |
| Current medical problems Respiratory failure Fever of unknown origin Acute renal failure Shock Complications of surgical procedures or medical care |
1,815 (48.2%) 576 (15.3%) 1,531 (40.7%) 829 (22.0%) 1,209 (32.1%) |
| Comorbidities during admission Myocardial infarction Congestive heart failure Peripheral vascular disease Cerebrovascular disease Dementia Chronic pulmonary disease Liver disease Diabetes Malignancy |
382 (10.2%) 1,199 (31.9%) 720 (19.1%) 659 (17.5%) 494 (13.1%) 1,620 (43.1%) 341 (9.1%) 1,741(46.3%) 675 (17.9%) |
| Healthcare exposures in the 90 days prior to admission Hospitalization Nursing home Intensive care |
1,784 (47.4%) 264 (7.0%) 682 (18.1%) |
| Antibiotics in the 90 days prior to admission | 2,374 (63.1%) |
| P. aeruginosa culture in the 90 days prior to admission | 859 (22.8%) |
| Hospital-acquired infectiona | 472 (12.5%) |
| Infection diagnoses during admissionb Bacterial infection of an unspecified site Skin and subcutaneous infection Ulcers Intraabdominal infection Urinary tract infection Osteomyelitis Chronic osteomyelitis Pneumonia Septicemia |
2,587 (68.8%) 674 (17.9%) 1,755 (46.6%) 421 (11.2%) 2,107 (56.0%) 726 (19.3%) 439 (11.7%) 1,676 (44.5%) 1,924 (51.1%) |
| Initial susceptible treatmentc | 1,259 (33.5%) |
a
Hospital-acquired infection was defined as a culture taken >2 days after admission and no previous P. aeruginosa culture in the 90 days prior to admission.
b
Infection diagnoses during admission are not mutually exclusive. Patients may have had more than one infection diagnosis during the admission.
c
Initial susceptible treatment was defined as receipt of at least one susceptible antibiotic treatment within 48 h of the index culture date.