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. 2022 Aug 18;10(5):e00322-22. doi: 10.1128/spectrum.00322-22

TABLE 4.

The detection performance of microfluidic chip-based LAMP amplification method for discriminating CPO from non-CPO directly from positive BCs

Bacteria Total (n) Carb posa (n) Carb negb (n) Accuracy
[95% CIc]
Sensitivity
[95% CI]
Specificity
[95% CI]
PPVd
[95% CI]
NPVe
[95% CI]
Total 133 18 115 94.0 [88.4–97.1] 100.0 [73.2–100.0] 93.2 [86.7–96.8] 63.6 [40.8–82.0] 100.0 [95.8–100.0]
Enterobacteriaceae 112 14 98 95.5 [89.7–98.3] 100.0 [70.0–100.0] 95.0 [88.2–98.1] 70.6 [44.1–88.6] 100.0 [95.2–100.0]
Non-fermentative 21 4 17 85.7 [64.5–95.9] 100.0 [19.8–100.0] 84.2 [59.5–95.8] 40.0 [7.0–82.9] 100.0 [75.9–100.0]

aCarb Pos: Carbapenemase positive.

b

Carb Neg: Carbapenemase negative.

c

95% CI: 95% confidence interval.

d

PPV: Positive predictive value.

e

NPV: Negative predictive value.