TABLE 4.
The detection performance of microfluidic chip-based LAMP amplification method for discriminating CPO from non-CPO directly from positive BCs
Bacteria | Total (n) | Carb posa (n) | Carb negb (n) | Accuracy [95% CIc] |
Sensitivity [95% CI] |
Specificity [95% CI] |
PPVd [95% CI] |
NPVe [95% CI] |
---|---|---|---|---|---|---|---|---|
Total | 133 | 18 | 115 | 94.0 [88.4–97.1] | 100.0 [73.2–100.0] | 93.2 [86.7–96.8] | 63.6 [40.8–82.0] | 100.0 [95.8–100.0] |
Enterobacteriaceae | 112 | 14 | 98 | 95.5 [89.7–98.3] | 100.0 [70.0–100.0] | 95.0 [88.2–98.1] | 70.6 [44.1–88.6] | 100.0 [95.2–100.0] |
Non-fermentative | 21 | 4 | 17 | 85.7 [64.5–95.9] | 100.0 [19.8–100.0] | 84.2 [59.5–95.8] | 40.0 [7.0–82.9] | 100.0 [75.9–100.0] |
aCarb Pos: Carbapenemase positive.
Carb Neg: Carbapenemase negative.
95% CI: 95% confidence interval.
PPV: Positive predictive value.
NPV: Negative predictive value.