TABLE 1.
In vitro susceptibility of G+ bacteria, G− bacteria and fungus to analog peptidesa
Peptides | MICb (μg/mL) |
||||||
---|---|---|---|---|---|---|---|
C. albicans | S. aureus | B. subtilis | E. coli | K. pneumoniae | P. aeruginosa | A. baumannii | |
MAF-1A | 600 | >1,200 | >1,200 | >1,200 | >1,200 | >1,200 | >1,200 |
Mt6 | 192 | 256 | 256 | 16 | 8 | 32 | 8 |
D-Mt6 | 128 | >256 | 128 | 8 | 8 | 16 | 8 |
Polymyxin B | -c | - | - | 2 | 2 | 8 | 2 |
The values are the means of three independent experiments performed in four replicates.
MIC was defined as the minimal peptide concentration required for the total inhibition of microbe growth in a liquid medium.
-, Not measured.