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. 2022 Oct 20;23(20):12622. doi: 10.3390/ijms232012622

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Chemical structures of clinically used retinoids from each generation. 2D-Structures taken from Pubchem.com. Available online: https://pubchem.ncbi.nlm.nih.gov/compound/Retinol#section=2D-Structure (accessed on 19 September 2022); https://pubchem.ncbi.nlm.nih.gov/compound/Tretinoin#section=2D-Structure (accessed on 19 September 2022); https://pubchem.ncbi.nlm.nih.gov/compound/Alitretinoin (accessed on 19 September 2022); https://pubchem.ncbi.nlm.nih.gov/compound/Isotretinoin#section=2D-Structure (accessed on 19 September 2022); https://pubchem.ncbi.nlm.nih.gov/compound/Etretinate (accessed on 19 September 2022); https://pubchem.ncbi.nlm.nih.gov/compound/Acitretin#section=2D-Structure (accessed on 19 September 2022); https://pubchem.ncbi.nlm.nih.gov/compound/Bexarotene#section=2D-Structure (accessed on 19 September 2022); https://pubchem.ncbi.nlm.nih.gov/compound/Tazarotene#section=2D-Structure (accessed on 19 September 2022); https://pubchem.ncbi.nlm.nih.gov/compound/Adapalene#section=2D-Structure (accessed on 19 September 2022); https://pubchem.ncbi.nlm.nih.gov/compound/Fenretinide#section=2D-Structure (accessed on 19 September 2022); https://pubchem.ncbi.nlm.nih.gov/compound/Trifarotene#section=2D-Structure (accessed on 19 September 2022). Figure generated with Biorender.com.