Table 3.

mTOR kinase inhibitors with therapeutic effects in cancer confirmed both in vitro and in vivo.

mTOR Kinase Inhibitors	Drugs	References
Dual inhibitors of mTOR/PtdIns–kinase	NVPBEZ235	[197]
	SF1126	[198,199]
	GSK2126458	[187,200]
	BGT226	[201,202]
	GDC0980	[203,204,205]
mTORC1/mTORC2 dual inhibitors	OSI027	[193,206,207]
	INK128	[208,209]
	AZD2014	[210,211,212]