TABLE 3.

The 25 most significant mutations and their positions in SARS-CoV-2 genomes

No.	Position	Gene	No. of sequencesa
1	241	5′ UTR	50,771
2	23403	Spike	50,229
3	3037	ORF1ab	50,121
4	14408	ORF1ab	49,840
5	25563	ORF3a	26,178
6	1059	ORF1ab	22,316
7	28881	Nucleocapsid	16,940
8	28883	Nucleocapsid	16,872
9	28882	Nucleocapsid	16,858
10	27964	ORF1ab	10,985
11	1163	ORF1ab	9,098
12	10319	ORF1ab	8,882
13	18555	ORF1ab	8,772
14	28869	Nucleocapsid	8,770
15	16647	ORF1ab	8,755
16	23401	Spike	8,746
17	7540	ORF1ab	8,729
18	18424	ORF1ab	8,758
19	28472	Nucleocapsid	8,572
20	21304	ORF1ab	8,320
21	25907	ORF3a	8,236
22	22992	Spike	8,146
23	19	5′ UTR	6,637
24	15	5′ UTR	5,662
25	13	5′ UTR	5,069

^aNumber of genomic sequences in which the mutation in present.