Table 1.

Mechanistic implications and role of αvβ6 upon expression in different cancers.

Cancer	Functions
Endometrial	Promotes invasiveness [41]
Basal Cell	Promotes invasiveness [42]
Liver	Poor prognosis [43]
Colon Cancer	Involved in cell adhesion and migration, activation of TGF-B, regulation of extracellular proteases, poor prognosis marker and implications in cancer metastasis to liver [43,44,45,46,47,48]
Gastric	Prognostic marker [49]
Cervical Squamous	Unfavourable marker [50]
Oral SCC	Increased expression in invasive stage of the cancer, regulation of migration and adhesion of cancer cells [51,52,53]
Pancreatic	Enhanced expression, regulation of tumour angiogenesis [54,55]
Breast	EMT induction and invasiveness [56,57]
Ovary	Enhanced expression leads to promotion of metastasis [58,59]