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. 2022 Oct 21;23(20):12676. doi: 10.3390/ijms232012676

Table 1.

Chemical structures of CK1 inhibitors included in the screening phase, their IC50 against CK1 δ/ε, and the percentage of activity of the kinase ULK1.

Compound Structure Cellular Assay CK1δ/ε
IC50 (nM) [18]
ULK1 %Inhn@10 μM
IGS2.7 graphic file with name ijms-23-12676-i001.jpg graphic file with name ijms-23-12676-i002.jpg 23/840 59 [18]
IGS3.27 graphic file with name ijms-23-12676-i003.jpg graphic file with name ijms-23-12676-i004.jpg 47/750 11.4
IGS3.4 graphic file with name ijms-23-12676-i005.jpg graphic file with name ijms-23-12676-i006.jpg 83/880 9