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. 2022 Oct 14;23(20):12319. doi: 10.3390/ijms232012319

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Prospective treatments for uterine factor infertility: (A) Histoanatomy of the uterus. The highly vascularized endometrium is covered by a columnar epithelium atop a stroma containing many glands and lies above the muscular myometrium. (B) Uterine transplant (UTx) is emerging as a potential treatment for uterine factor infertility. A live or cadaveric donor (blue) uterus is transplanted to the patient (pink) who takes antirejection drugs until childbearing is finished. (C) Tissue engineering could restore uterine function. Murine models have restored uterine function by seeding a decellularized uterus with autologous uterine cells. Numbers indicate procedure order Figure created with BioRender.com.