Table 2.

Summary of tissue-engineering uterus models in vivo.

Reference.	Tissue	Host	Scaffold	Cells	Time In Vitro	Time In Vivo	Time of Conception	Gestation Achieved
Santoso et el. 2014 [78]	full thickness uterine patch	rat	decellularized rat uterus	acellular	n/a	≤51 days	30 days	late-stage
Miyazaki & Maruyama 2014 [79]	full thickness uterine patch	rat	decellularized rat uterus	rat neonatal, adult uterine cells and rat BM-MSCs	≤10 days	≤90 days	28 days	late-stage
Ding et al. 2014 [82]	full thickness uterine patch	rat	collagen	rat BM-MSCs	72 h	105–109 days	90 days	late-stage
Hellström et al. 2016 [80]	full thickness uterine patch	rat	decellularized rat uterus	rat uterus primary cells and rat mscs	3 days	9 weeks	6 weeks	late-stage
Hiraoka et al. 2016 [81]	full thickness uterine patch	mouse	decellularized mouse uterus	acellular	n/a	≤7 weeks	4 weeks	full term
Campbell et al. 2008 [83]	full thickness uterine horn tip	rat	boiled blood clots	uncontrolled host cellularization	in vivo 2 weeks	4–12 weeks	4,6,12 weeks	late-stage
Magalhaes et al. 2020 [84]	subtotal uterus	rabbit	PGA/PLGA	rabbit primary endometrial and myometrial cells	--	≤7 months	6 months	full term