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Anti-diabetic effects of esculetin: Esculetin downregulates the expression of PPARγ, H3S10phospho, H3S28phospho, H3K9Ac, H3K4me2, and H3K9me2, hyperacetylation of histone H3 lysine (K) 14 and 18 and attenuates diabetes and its associated complications. ↑: Overexpression; ⊣: inhibition. •: RBC; •: Sugar.
