HCC |
Hepatocellular Carcinoma |
HSC |
Hepatic Stellate Cells |
NASH |
Nonalcoholic Steatohepatitis |
IR |
Insulin Resistance |
FFA |
Free Fatty Acids |
MMPs |
Metalloproteinases |
ECM |
Extracellular Matrix Protein |
LSECs |
Liver Sinusoidal Endothelial Cells |
TIMPs |
Tissue Inhibitors of MMPs |
LFC |
Liver Fat Content |
FGF |
Fibroblast growth factor |
HFF |
Hepatic Fat Fraction |
THR |
Thyroid Hormone Receptor |
FXR |
Farnesoid X Receptor |
VLDL |
Very Low-density Lipoprotein |
HDL |
High-density Lipoprotein |
PPARs |
Peroxisomal Proliferator-activated Receptors |
GLP-1 |
Glucagon-like Peptide-1 |
GIP |
Gastric Inhibitory Polypeptide |
CCR2 |
C-C chemokine receptor 2 |
MPC |
Mitochondrial Pyruvate Carrier |
ALD |
Alcoholic Liver Disease |
HVPG |
Hepatic Venous Pressure Gradient |
HSP47 |
Heat Shock Protein 47 |
siRNA |
Small Interfering RNA |
ACE-1 |
Angiotensin-I Converting Enzyme 1 |
AT-II |
Angiotensin-II |
RAS |
Renin-angiotensin System |
ADCC |
Antibody-dependent Cellular Cytotoxicity |
PDGF |
Platelet-derived Growth Factor |
VEGF |
Vascular Endothelial Growth Factor |
FGF |
Fibroblast Growth Factor |
EGF |
Epidermal Growth Factor |
PVP |
Portal Vein Pressure |
MCD |
Methionine and Choline-deficient Diet |
ROS |
Reactive Oxygen Species |
HFD |
High-Fat Diet |
CYP2E1 |
Cytochrome P450 2E1 |
HA |
Hyaluronic Acid |
Bcl-2 |
B-cell Lymphoma-2 |
HFHS |
High-Fat High-Sucrose |
ALP |
Alkaline Phosphatase |
a-SMA |
alpha-Smooth Muscle Actin |
TGF-b1 |
Transforming Growth Factor-b 1 |
CDAA |
Choline-deficient-amino-acid–defined |
CPT-1 |
Carnitine Palmitoyl Transferase-1 |
ASGPR |
Asialoglycoprotein Receptor |
Chol |
Cholesterol |
IGF2R |
Insulin-like Growth Factor 2 Receptor |
CD44 |
Cluster of Differentiation 44 |
RBP |
Retinol-binding Protein |
TRAIL |
TNF-related Apoptosis-inducing Ligand |
NPs |
Nanoparticles |
cRGD |
cyclic RGD |
LNPs |
Lipid Nanoparticles |