TABLE 3.
Prevalence of Pfdhps-Pfdhfr haplotypes in P. falciparum isolates imported to Zhejiang Province from Nigeria
| Haplotype | Codona | No. of isolates (%) |
|---|---|---|
| Single mutant | NCNDI-ISAKAA | 2 (1.42) |
| Double mutant | NRNDI-ISAKAA | 1 (0.71) |
| Triple mutant | ICNDI-ISGKAA | 3 (2.13) |
| IRNDI-ISAKAA | 3 (2.13) | |
| NRNDI-IAAKAA | 1 (0.71) | |
| Quadruple mutant | IRNDI-ISGKAA | 48 (34.04) |
| IRNDI-IAAKAA | 7 (4.96) | |
| IRNDI-ISAKAS | 1 (0.71) | |
| ICNDI-VSGKAA | 1 (0.71) | |
| NCSDI-VAGKAS | 1 (0.71) | |
| Quintuple mutant | IRNDI-IAGKAA | 16 (11.35) |
| IRNDI-ISGEAA | 8 (5.67) | |
| IRNDI-ISGKAS | 4 (2.84) | |
| IRNDI-VSGKAA | 1 (0.71) | |
| NRNDI-IAGKAS | 1 (0.71) | |
| Sextuple mutant | IRNDI-IAGKAS | 10 (7.09) |
| IRNDI-ISGKGS | 2 (1.42) | |
| IRNDI-VAGKAA | 3 (2.13) | |
| IRNDI-VSGKAS | 1 (0.71) | |
| IRNDI-VSGKGA | 2 (1.42) | |
| Septuple mutant | IRNDI-VAGKAS | 1 (0.71) |
| IRNDI-VAGKGA | 1 (0.71) | |
| IRNDI-IAGKGS | 1 (0.71) | |
| Octuple mutant | IRNDI-VAGKGS | 22 (15.60) |
| Total | 141 (100.00) | |
a
The underlined amino acid of the haplotypes indicated that it was mutant.