Table 1.

Characteristics of renal amyloidoses [21,31,49,50,51,52].

Amyloidogenic Protein	Sporadic (S) or Hereditary (H)/Local (L) or Systemic (S)	Overall Incidence/Prevalence of Kidney Impairment, %	Extrarenal Manifestation (Other Organ Tropism)
Ig light chains	S/S	59/53–86	Different organs
Serum amyloid A protein	S/S	2.9/7–40	Different organs
Leukocyte cell-derived chemotaxin-2	S/S	3.1/2.5–19.1	Liver, lungs, spleen, adrenal glands, prostate, gastrointestinal tract, gall bladder
Ig heavy chains	S/S	2.3/0.3–4.6	Different organs
Ig light and heavy chains	S/S	not assessed/3.6	Different organs
Fibrinogen α chain	H/S	0.44/1.3–3.5	Liver, spleen, gastrointestinal tract, fat
Transthyretin	S/S; H/S	28/0.9–1.4	Different organs with heart and peripheral nervous system predominance
Apolipoprotein A–IV	H/S	0.35/0.1–1.06	Heart, gastrointestinal tract, skin, lungs
Gelsolin	H/S	0.18/0.8	Cranial nerves, cornea, liver, gastrointestinal tract, skin, heart, breast, pituitary gland
Apolipoprotein C–II	H/L	<0.1/0.6	-
Apolipoprotein A–I	H/S	0.35/0.1–0.5	Liver, heart, skin, larynx, gastrointestinal tract, muscles, peripheral nervous system
Lysozyme	H/S	<0.1/0.16	Lymphatic nodes, liver, gastrointestinal tract, lungs, fat, heart
Apolipoprotein A–II	H/L	<0.1/<0.1 (extremely rare)	-
Apolipoprotein C–III	H/S	<0.1/<0.1 (extremely rare)	Liver, heart, spleen
Calcitonin	S/S	<0.1/<0.1 (extremely rare)	Thyroid gland, fat