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. 2022 Oct 18;23(20):12444. doi: 10.3390/ijms232012444

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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ASPHmod-pulsed moDCs induce an increase in CD4⁺CD154⁺TNF-α⁺ T cells. (A) Representative flow cytometric analysis of a single individual. (B) Data represent the means ± SD of the same individual assessed in quintuplicate: **** significantly different, p < 0.001 (one-way ANOVA). (C) Fold change in CD4⁺CD154⁺TNF-α⁺ T cells relative to cells restimulated with the non-pulsed moDC control. Data represent the means ± SD of nine individuals: * significantly greater, p < 0.05 (unpaired Student’s t test). (D) Relative T cell response of each individual to ASPH- versus ASPHmod-pulsed moDCs.