TABLE 1.

Mean logarithmic titers obtained by flow assay, killing assay, and ELISA for antisera from adults vaccinated with pneumococcal PS or conjugate vaccine

Vaccine	Serotype	n	MLTa obtained by:
			Flow assay		Killing assay		ELISA
			Pre	Post	Pre	Post	Pre	Post
23-valent PS	6A	23	NDb	0.21	ND	2.41	ND	2.30
	6B	23	ND	0.37	ND	2.77	ND	1.15
	19F	23	ND	0.83	ND	2.64	ND	1.13
Bivalent conjugate	23F	46c	0.25	1.32	0.23	2.53	0.52	2.12
Tetravalent conjugate	6B	34	0.25	1.07	1.28	3.50	0.27	1.31
	19F	40	0.29	0.34	0.92	2.63	0.39	1.59
	23F	40	0.21	0.62	0.88	2.85	0.33	1.54

^aMean log₁₀ titers (MLT) were calculated before vaccination (Pre) for conjugate antisera only and after vaccination (Post) for both PS and conjugate vaccine antisera. 

^bND, not done, because antisera were not available. 

^cMLT for the killing assay was calculated for seven prevaccination and seven postvaccination antisera.