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(A)—The crystal structure of the EcoRK dimer (PDB 1RKD). (B)—The mobility of the lid domain during the transition from APO form (semi-transparent, spatial alignment with crystal structure of APO EcoRK, PDB 1RKA) to substrate-bound form (PDB 1RKD). The lid domain is represented as cartoon, all other residues—as a surface.
