Table 2.
Minimum Inhibitory Concentrations of polyaminoisoprenyl derivatives 3–6 against various Gram-negative bacterial strains.
| MIC (µM) (µg/mL) | ||||
|---|---|---|---|---|
| Strains | Cpd 3 | Cpd 4 | Cpd 5 | Cpd 6 |
| P. aeruginosa PA01 | 25 (10) | 200 (78) | >400 (>135) | >400 (>130) |
| E. coli ATCC 25922 | 50 (20) | 200 (78) | >200 (>67) | >200 (>65) |
| K. pneumoniae ATCC 13883 | 50 (20) | 200 (78) | >200 (>67) | >200 (>65) |
| C. koseri IP8294 | 50 (20) | 200 (78) | >200 (>67) | >200 (>65) |
| E. cloacae DSM 129 | 50 (20) | 200 (78) | >200 (>67) | >200 (>65) |
| K. aerogenes ATCC 13048 | 100 (40) | >400 (>156) | >400 (>135) | >400 (>130) |
| K. aerogenes 289 | 100 (40) | >400 (>156) | >400 (>135) | >400 (>130) |
| AG100A_pUC18 | 12.5 (5) | 50 (19) | 100 (33) | >200 (>65) |