Abbreviation	Full Name
25HC	25-hydroxycholesterol
5-MTHF	5-methyltetrahydrofolate
ACE2	angiotensin-converting enzyme 2
ACHR	artificial centering hit-and-run
ACTZ	acetazolamide
AKG	α-ketoglutarate
ALDOA	fructose bisphosphonate aldolase A
AMPK	AMP-activated protein kinase
ATG5	autophagy-related gene 5
C	complement
CA2	carbonic anhydrases 2
CMPK2	cytidine/uridine monophosphate kinase 2
COVID-19	coronavirus disease 2019
cPLA2	cytoplasmic phospholipase A2
CYP1B1	cytochrome P450 family 1 subfamily B member 1
DEG	differentially expressed gene
DHF	dihydrofolate
EZA	ethoxzolamide
FA	folate
FASN	fatty acid synthase
FBA	flux balance analysis
FR	folate transport-related receptor
GAPDH	glycoraldehyde-3-phosphate dehydrogenase
GAPDH	glyceraldehyde-3-phosphate dehydrogenase
GLB1	galactosidase β 1
GLB1	galactosidase beta 1
GLTP	glycolipid transfer protein
GO	gene ontology
GPR	Gene-Protein-Reaction rules
GSEA	gene set enrichment analysis
GSH	reduced glutathione
GSMM	genome-scale metabolic model
GSR	glutathione-disulfide reductase
GSSG	oxidized glutathione
HDLBP	high-density lipoprotein-binding protein
HIV	human immunodeficiency virus
HLA-DR	human leukocyte antigen D-related
HMG-CoA	3-hydroxy-3-methylglutaryl-coenzyme A
HMR	human metabolic reactions
IFN	interferon
IFN-γ	Interferon-γ
IL	interleukin
IL-6	interleukin-6
LacCer	lactosylceramide
lb	lower boundaries
LDHA	lactate dehydrogenase A
LPS	lipopolysaccharide
LTF	lactotransferrin
MAS	malate-aspartate shuttle
MERS-CoV	Middle East respiratory syndrome coronavirus
MeV	measles virus
MPO	myeloperoxidase
mTORC1	mechanistic target of rapamycin complex 1
MTX	methotrexate
MZB1	marginal zone B and B1 cell specific protein
NES	normalized enrichment scores
noxPPP	non-oxidative phase PPP
NPC1	Niemann-Pick C intracellular cholesterol transporter 1
Nrf2	nuclear factor E2-related factor 2
OXPHOS	oxidative phosphorylation
oxPPP	oxidative phase PPP
PaO2	arterial partial pressure of blood oxygen
PBMCs	peripheral blood mononuclear cells
PECAM-1	platelet/endothelial cell adhesion molecule-1
PFK	phosphofructokinase
PGAM	phosphoglycerate mutase
PKM	pyruvate kinase M1/2
PPP	pentose phosphate pathway
RAR-α	alpha retinoic acid receptor
RIG-I	retinoid-induced gene I
RNASE2	ribonuclease A family member 2
ROS	reactive oxygen species
SARS-CoV-2	severe acute respiratory syndrome coronavirus-2
scRNA-Seq	single-cell RNA-Seq
SDH	succinate dehydrogenase
SLC	solute carrier
SLC2A3	solute carrier family 2 member 3
SREBP	sterol regulatory element-binding proteins
SRF	severe respiratory failure
TCA	tricarboxylic acid cycle
TPM	transcript per million
TXNDC5	thioredoxin domain containing 5
ub	upper boundaries