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. 2022 Oct 18;23(20):12491. doi: 10.3390/ijms232012491
α linear term of the linear-quadratic model of clonogenic survival
αref α for the reference photon exposure
ß quadratic term of the linear-quadratic model of clonogenic survival
ß ref ß for the reference photon exposure
DNA deoxyribonucleic acid
DSB double strand break
LEM local effect model [6]
LEM IV fourth version of the local effect model [26]
LET linear energy transfer
LQM linear-quadratic model of clonogenic survival [17,18]
MBM mixed beam model [7]
MCF Mayo Clinic Florida, Jacksonville, Florida, United States of America
MCF MKM Mayo Clinic Florida microdosimetric kinetic model [33]
MKM microdosimetric kinetic model [5]
modified MKM modified microdosimetric kinetic model [9]
non-Poisson MKM corrected version of the original microdosimetric kinetic model to account for the non-Poisson distribution of lethal lesions [8]
PHITS Particle and Heavy Ion Transport code System [75]
PIDE Particle Irradiation Data Ensemble [29,34]
RBE relative biological effectiveness
RBES in vitro clonogenic cell survival RBE for the surviving fraction S
r d mean radius of the subnuclear domains
R n mean radius of the cell nucleus