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Tumor stroma in thyroid cancer. Papillary thyroid carcinoma (PTC) shows desmoplastic tumor stroma mainly composed of caner-associated fibroblasts (CAF) (×100) (a). Prominent immune cells are noted in PTC subtype such as Warthin-like variant (×100) (b). Fibrous stroma composed of CAF is noted in anaplastic thyroid carcinoma (×100) (c). Immune cells stroma is present in poorly differentiated thyroid carcinoma (×100) (d).
