Table 1.

Nutritional deficiencies in neurodegenerative disorders.

Nutrient	Report of Deficiency	Ref No.
Coenzyme Q10	Deficiency in cerebral cortex CoQ10 status in PD patients Reduced CoQ10 in plasma and platelets in PD patients Depleted levels of CoQ10 in blood associated with development of AD Reduced CoQ10 in plasma or postmortem brain tissue of MSA patients	[18,19] [20,21] [22] [23,24,25]
Selenium	Se deficiency in brain tissue in PD patients Depleted Se levels in blood or brain tissue in AD Se blood levels inversely associated with ALS	[26] [27,28] [29,30]
B-vitamins/NADH	Reduced B1 levels in blood and CSF fluid in PD patients B1 deficiency in blood and autopsied brain samples from AD patients B1 levels depleted in blood and CSF in ALS Reduced blood B2 levels associated with developing ALS Reduced blood B2 in PD patients Reduced blood B2 in AD patients Reduced B3 (niacin) in PD Niacin intake inversely related to development of AD	[31,32,33] [34] [35,36] [37] [38] [39,40] [41] [42]
l-carnitine/acetyl-l-carnitine	Reduced blood levels in PD Reduced CSF levels in AD Reduced levels of carnitine acetyltransferase in postmortem brain tissue of AD patients	[43,44,45] [46] [47]
PVitamin D3	Depleted D3 blood levels and increased risk of PD Depleted D3 blood levels and increased risk of AD Depleted D3 blood levels and increased risk of ALS D3 deficiency reported in MSA	[48] [49,50] [51] [52,53]