Table 1.
List of studies evaluating the role of transaminases on outcomes after transarterial chemoembolization.
First Author, Year | N | UninodularDisease (%) | Child–Pugh A (%) | Post-TACE Syndrome (%) | Role of Transaminases |
---|---|---|---|---|---|
Granito, 2022 [10] | 70 | 61.5% | 84.3% | 31.4% | AST and/or ALT increase >50% from baseline were independent predictors of complete radiological response |
Jia, 2022 [14] and Nam, 2020 [16] | 1336 | NR | 83.6% | NR | The ASARA score, which includes AST, predicts overall survival after TACE |
Tang, 2018 [11] | 315 | 20.3% | 98.8% | NR | AST-to-platelet ratio predicted radiological response |
Zhu, 2018 [12] | 351 | 86.3% | 78.6% | NR | AST-to-platelet ratio and ALT predicted disease-free survival |
Liu, 2017 [17] | 760 | 41.2% | 81.7% | NR | AST-to-ALT ratio predicts overall survival. |
Ha, 2016 [15] | 153 | 25.5% | 76.5% | NR | The ART score, which includes AST, predicted overall survival |
Yang, 2015 [13] | 189 | 58.7% | 87.3% | NR | AST-lymphocyte ratio index independently associated with overall survival |
AST: aspartate aminotransferase; ALT; alanine aminotransferase; NR: not reported; TACE: Transarterial chemoembolization.