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editorial
. 2022 Oct 6;12(10):1663. doi: 10.3390/jpm12101663

Table 1.

List of studies evaluating the role of transaminases on outcomes after transarterial chemoembolization.

First Author, Year N UninodularDisease (%) Child–Pugh A (%) Post-TACE Syndrome (%) Role of Transaminases
Granito, 2022 [10] 70 61.5% 84.3% 31.4% AST and/or ALT increase >50% from baseline were independent predictors of complete radiological response
Jia, 2022 [14] and Nam, 2020 [16] 1336 NR 83.6% NR The ASARA score, which includes AST, predicts overall survival after TACE
Tang, 2018 [11] 315 20.3% 98.8% NR AST-to-platelet ratio predicted radiological response
Zhu, 2018 [12] 351 86.3% 78.6% NR AST-to-platelet ratio and ALT predicted disease-free survival
Liu, 2017 [17] 760 41.2% 81.7% NR AST-to-ALT ratio predicts overall survival.
Ha, 2016 [15] 153 25.5% 76.5% NR The ART score, which includes AST, predicted overall survival
Yang, 2015 [13] 189 58.7% 87.3% NR AST-lymphocyte ratio index independently associated with overall survival

AST: aspartate aminotransferase; ALT; alanine aminotransferase; NR: not reported; TACE: Transarterial chemoembolization.