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. 2022 Oct 14;12(10):1719. doi: 10.3390/jpm12101719

Table 1.

Reward Deficiency Syndrome Criteria.

GARS Score of 4 With 1–2 Criteria Mild
GARS Score of 4–6 with 3 or more Criteria Moderate
GARS Score of 7–9 with 1–2 Criteria Moderate
GARS Score of 7–9 with 3 or more Criteria Severe
GARS Score of 10 or more with 1–2 Criteria Severe
GARS Score of 10 or more with 3 or more Criteria Profound
Criteria Set ONE—DSM-5 Disorders
A present diagnosis, past diagnosis, or history of these behavioral disorders
Substance Use Process Disorders Disorders: Alcohol Use Disorder, Opioid Use Disorder, Cannabis Use Disorder; Sedative, Hypnotic, Anxiolytic Use Disorder; Cocaine Use Disorder, Amphetamine Use Disorder, Hallucinogen Use Disorder, Nicotine Use Disorder, Inhalant Use Disorder, Other, Unknown Substance Use Disorder
Specifiers: Mild, Moderate, Severe, Early Remission (6–12 months), Sustained Remission (12+ months), in a Controlled Environment, on Maintenance Therapy
Process Disorders Gambling, Sex, Other Specified Process Disorders
Depressive (and related) Disorders Major Depression, Dysthymia, Disruptive Mood Dysregulation, SUD/Medication/Medical Condition Induced Depressive Disorder, Disruptive Premenstrual Dysphoric Disorder
Anxiety Disorders Generalized Anxiety Disorder, Social Anxiety, Panic Attack
Disorder, Separation Anxiety, Selective Mutism, Specific Phobia,
SUD/Medication/Medical Condition Induced Anxiety
Trauma and Stress Disorders Reactive Attachment, Disinhibited Social Engagement, Post-Traumatic Stress Disorder (PTSD), Acute Stress Disorders
Disruptive, Impulse Control, and Conduct Disorders Oppositional Defiant Disorder, Intermittent Explosive Disorder, Conduct Disorder, Pyromania, Kleptomania
Personality Disorders General Personality Disorder, Paranoid Personality Disorder, Schizoid/Schizotypal Personality Disorder, Anti-Social Personality Disorder, Borderline Personality Disorder, Histrionic Personality Disorder, Narcissistic, Personality Disorder, Avoidant Personality Disorder, Dependent Personality Disorder
Obsessive Compulsive Disorders and Related Disorders Trichotillomania, Excoriation Disorder, SUD/Medical/Medication Induced Obsessive Compulsive Disorder (OCD), other Medical Condition, Induced Personality Disorder
Schizophrenic Disorders Schizophrenic Disorders: Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder, Delusional Disorder, Brief Psychotic Disorder, MH/Medical Catalonia, SUD/Medication/Medical Condition Induced Psychotic Disorder
Dissociative Disorders Dissociative Identity Disorder, Dissociative Amnesia, Depersonalization/Derealization Disorder
Other Not Otherwise Specified (NOS) Disorders Gender Dysphoric Disorder
Paraphilic Disorders
Spectrum Disorders Attention Deficient Disorder, Attention Deficient/Hyperactivity Disorder, Tourette’s Syndrome Autism
Criteria Set TWO
Reported history of these symptoms:
Novelty seeking This trait is associated with exploratory activity in response to novel stimulation, impulsive decision making, extravagance in approach to reward cues, quick loss of temper, and avoidance of frustration.
Impulsivity The construct of impulsivity includes at least two independent components: first, acting without an appropriate amount of deliberation, which may or may not be functional; and second, choosing short-term gains over long-term ones.
Difficulty feeling reward (Anhedonia) Either a reduced ability to experience pleasure or a diminished interest in engaging in pleasurable activities.
Motivational Anhedonia Decrease in motivation to participate in pleasurable activities
Rumination, Obsessive, and Intrusive Negative Thoughts Possible causes and consequences, as opposed to its solutions