Table 6.
Parameters | Colchicine (n = 113) |
Placebo (n = 127) |
p |
---|---|---|---|
Postoperative day 3 | |||
WBC, 10×9/L | 11.4 (9.5; 14.2) | 12 (9.6; 14.6) | 0.284 |
Neutrophils, 10×9/L | 8.8 (6.7; 12) | 8.9 (7.8; 12.7) | 0.536 |
Neutrophils, % | 77 (71; 84) | 79 (72; 82) | 0.901 |
Platelets,10×9/L | 189 (160; 237) | 199 (162; 254) | 0.442 |
Creatinine, mcmol/L | 72 (65; 82) | 75 (66.7; 88.5) | 0.065 |
eGFR | 107 (90; 119) | 100 (84; 124) | 0.216 |
Glucose, mmol/L | 7 (5.7; 8.6) | 6.6 (5.7; 8.3) | 0.441 |
AST, IU/L | 31 (24; 45) | 31 (21; 40) | 0.494 |
ALT, IU/L | 20 (14; 30) | 21 (13; 29) | 0.995 |
Potassium, mmol/L | 4.1 (3.8; 4.3) | 4.2 (3.9; 4.5) | 0.056 |
Postoperative day 5 | |||
WBC, 10×9/L | 9.3 (8; 11) | 10.9 (8.4; 13.2) | 0.003 |
Neutrophils, 10×9/L | 5.9 (4.7; 7.5) | 6.8 (5; 9.4) | 0.014 |
Neutrophils, % | 62 (58.6; 68.9) | 63 (57; 68) | 0.982 |
Platelets, 10×9/L | 265 (211; 314) | 262 (217; 339) | 0.631 |
Creatinine, mcmol/L | 75 (68; 83) | 77 (68; 86) | 0.566 |
eGFR | 103 (85; 119) | 100 (82; 127) | 0.755 |
Glucose, mmol/L | 6.4 (5.3; 7.4) | 5.9 (5.3; 7.3) | 0.905 |
AST, IU/L | 28 (22; 34) | 29 (20; 38) | 0.885 |
ALT, IU/L | 28 (20; 42) | 27 (17; 46) | 0.886 |
Potassium, mmol/L | 4.1 (3.7; 4.4) | 4.3 (4; 4.6) | 0.011 |
WBC—white blood cell count, eGFR—estimated glomerular filtration rate, AST—aspartate aminotransferase, ALT—alanine aminotransferase.