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. 2022 Oct 14;12(10):1605. doi: 10.3390/life12101605
3CLpro 3C-like protease
ACE2 angiotensin-converting enzyme 2
ADAM17 ADAM metallopeptidase domain 17
Ang angiotensin
ARDS acute respiratory distress syndrome
cGMP cyclic guanosine monophosphate
COVID-19 coronavirus disease 2019
CRS cytokine-release syndrome
DIC disseminated intravascular coagulation
E envelope
ECs endothelial cells
ED endothelial dysfunction
HIF-1α hypoxia-inducible factor 1α
ICAM-1 intracellular adhesion molecule 1
ICU intensive care unit
INFγ
IV
Interferon-γ
intravenous
LMWH low-molecular-weight heparin
M membrane-associated
MMP-2 matrix metalloproteinase 2
Mpro major protease inhibitor
N nucleocapsid
NETosis neutrophil extracellular traps
NF-κB nuclear factor κB
NO nitric oxide
PAI-1 plasminogen activator inhibitor 1
PDGF platelet-derived growth factor
PFT pulmonary function test
POTS postural tachycardia syndrome
RAAS renin–angiotensin–aldosterone system
RBD receptor-binding domain
ROS reactive oxygen species
S spike
SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2
SDC1 syndecan-1
SpO2 peripheral oxygen saturation
sVCAM1 soluble vascular cell adhesion molecule 1
TF tissue factor
TLRs Toll-like receptors
TMPRSS-2 transmembrane protease serine protease-2
TNF tumor necrosis factor
uPA urokinase plasminogen activator
URTI upper respiratory tract infection
VEGF vascular endothelial growth factor
VWF von Willebrand factor
WHO World Health Organization