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. 2022 Sep 25;8(10):1005. doi: 10.3390/jof8101005

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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H&E-stained wound sections of (A) section in normal skin showed normal epidermal thickness (black arrow), with underlying dermis showing thick collagen bands (red arrows), hair follicles (green arrows), and sebaceous glands (blue arrows) (×200). (B) Section in the wound of the control group showed an ulcer (blue arrow) filled with hemorrhage (red arrow) and acute and chronic inflammatory cellular infiltrate (black arrow) (×200). (C) Section in the Betadine™-treated group showed partial epithelization (black arrow) with underlying granulation tissue (blue arrows) with little inflammatory cellular infiltrate (red arrow) (×200). (D) Section in the AgNPs-treated group showed complete epithelization (black arrows) with underlying focal granulation tissue formation (blue arrows) with adjacent proliferating hair follicles (red arrows) without inflammation (×200).