Table 1.
Main clinicodemographic data of patients with CHC included in the study (F: female; M: male; n: number).
| Author and Year | Country | Study Type | Patients | Follow-Up (Years) | Method of Assessment | Malignant Development (%) | |||
|---|---|---|---|---|---|---|---|---|---|
| n | Sex | Mean Age (Years) |
|||||||
| F | M | ||||||||
| Cawson, 1966 [7] | UK | Case series | 15 | 4 | 11 | 50.5 | 10 | Biopsy (P.A.S) | 13.3 |
| Williamson, 1969 [20] | UK | Case series | 2 | 0 | 2 | 59.5 | - | Biopsy (P.A.S), culture | 50 |
| Eyre & Nally, 1971 [23] | UK | Case report | 3 | 0 | 3 | 55.7 | - | Scraping and culture | 66.6 |
| Bánóczy, 1977 [21] | Hungary | Cohort | 70 | - | - | - | 9.8 | Biopsy (P.A.S) | 28.7 |
| Silverman et al., 1984 [26] | USA | Cohort | 80 | - | - | 54 | 7.2 | Biopsy (P.A.S), culture | 4.4 |
| Abdulrahim et al., 2013 [22] | Ireland | Case-control | 31 | 14 | 17 | 57.8 | 2 | Biopsy (P.A.S) | 6.5 |
| Chiang et al., 2020 [25] | Taiwan | Cohort | 22 | - | - | - | 5 | Biopsy (P.A.S), | 13.6 |
| McParland & Warnakulasuriya, 2021 [24] | UK | Descriptive | 3 | - | - | - | 16 | Biopsy (P.A.S), | 33.3 |
| Zhang et al., 2021 [6] | China | Cohort | 48 | 13 | 35 | 54.9 | 6 | Biopsy (P.A.S), | 4.2 |
| Total | 274 | 31 | 68 | 55.4 | 8 | - | 12.4 | ||