Table 2.
Multivariable Cox’s regression model.
| Parameter | Multivariable Analysis | |||
|---|---|---|---|---|
| HR | 95% CI | p | ||
| Age | 1.03 | 1.01 | 1.04 | <0.001 |
| Sex | ||||
| M (ref) | 1 | |||
| F | 0.76 | 0.55 | 1.03 | 0.079 |
| Respiratory rate | 1.08 | 1.06 | 1.11 | <0.001 |
| Respiratory severity scale | ||||
| None (ref) | 1 | |||
| Mask/glasses/cannula | 1.97 | 0.98 | 3.95 | 0.058 |
| NIV | 2.01 | 0.98 | 4.10 | 0.056 |
| OTI | 13.33 | 5.82 | 30.53 | <0.001 |
| GCS/15, n (%) | ||||
| Mild impaired consciousness (ref) | 1 | |||
| Moderate/severe impaired | 4.03 | 2.24 | 7.24 | <0.001 |
| consciousness | ||||
| Missing | 0.81 | 0.43 | 1.53 | 0.524 |
| Chronic cardiac disease | 1.39 | 1.00 | 1.92 | 0.047 |
| Antivirals | 0.43 | 0.27 | 0.68 | <0.001 |
| Stages of eGFR | ||||
| 1 (ref) | 1 | |||
| 2 | 1.71 | 1.08 | 2.70 | 0.022 |
| 3 | 2.94 | 1.76 | 4.91 | <0.001 |
| 4 | 3.68 | 1.90 | 7.12 | <0.001 |
| 5 | 7.25 | 4.04 | 13.01 | <0.001 |
Abbreviations: GCS: Glasgow coma score; NIV: non-invasive ventilation; OTI: orotracheal intubation; CKD: chronic kidney disease; CLD: chronic liver disease; eGFR: estimated glomerular filtration rate; Malign: malignancies. Chronic cardiac diseases (ischemic cardiopathy, previous acute myocardial infarction (AMI), heart failure, valvulopathy, and atrial fibrillation).