Figure 1.

The schema and mechanism of the VLf that emits violet light (VL). The pseudo-placebo (control) and VLf (A). The control eyeglasses emit a minimal irradiance of VL under 10 µW/cm² (control group, top of B) and VLf emit VL irradiance of 310 µW/cm² (VLf group, bottom of B). In the myopic patients with normal eyeglasses, the axial length is elongated with choroidal thinning (C). In the myopic patients with VLf, the axial length elongation is suppressed with choroidal thickening, presumably through OPN5-expressing retinal ganglion cells by emitting VL from the VLf frames, as was demonstrated in the mouse experience (D). VLf: violet light eyeglasses frames.