Fig 4. NY11 and NY2 RBD amplifications.

Overview of the SARS-COV-2 Spike RBD lineages identified from the NY11 and NY2 sewershed. Lineages designated A and B belong to two lineages groups that appear unrelated. Amino acid changes similar to (green boxes) or identical to (orange boxes) changes in Omicron (BA.1, BA.2 or BA.5) are indicated. Synonymous changes (syn) are indicated in gray. The major VOCs during this time period (Alpha, Beta, Gamma, BA.1 and BA.2) are indicated. The heatmap (right) illustrates lineage (row) detection by date (column), colored by the log₁₀ percent relative abundance of that lineage. Lineage detected in both sewersheds indicated with an asterisk. Uncondensed output in S6 and S7 Data.