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The anti-Sporothrix activity of olorofim. The chemical structure of olorofim (A). After exposure to olorofim or itraconazole, the yeast killing was evaluated by cultivation in a drug-free medium (B). The ability of olorofim to inhibit mature biofilms was determined according to the metabolic activity of cells in the presence of compounds (C). Results are shown as the mean of percent growth or metabolic activity and the standard error of the mean.
