Table 1.
Content of neutrophil granules and secretory vesicles.
| Function | Primary/ Azurophilic |
Secondary/ Specific |
Tertiary/ Gelatinase |
Secretory Vesicles |
|---|---|---|---|---|
| Microbicidal | Myeloperoxidase Lysozyme Defensins Cationic proteins Azurocidin Cap57 |
Lysozyme Lactoferrin Pentraxin 3 Lipocalin 2 Haptoglobin |
Cathelicidin Lysozyme |
|
| Serine proteases | Neutrophil elastase Cathepsins |
|||
| Metalloproteinases | Proteinases | Collagenase (MMP-8) | Gelatinase B (MMP-9) Leukolysin (MMP-25) Collagenase (MMP-8) |
Leukolysin (MMP-25) Proteinase 3 (myeloblastin) |
| Acid hydrolases | Cathepsins B β-glucuronidase Glycerophosphatase N-acetylglucosaminidase α-mannosidase |
β2-microglobulin | ||
| Others | Heparin binding protein (HBP) Sialidase Presenilin Granulophysin α1-antitrypsin |
Histaminase Heparanase Stomatin B12 binding protein Cytochrome b C3b receptor |
C3bi receptor | Heparin-binding protein (HBP) Plasma proteins (including albumin) Alkaline phosphatase |