Table 1.
Immunologic methods used for antigen or antibody detection for the diagnosis of the major endemic mycoses.
| Method | BLM | CDM | HPM | PCM | CRY | SPT | TLM |
|---|---|---|---|---|---|---|---|
| Complement fixation | Ab | Ab | Ab | Ab | - | - | - |
| Immunodiffusion | Ab | Ab/Ag | Ab | Ab | - | Ab | Ab/Ag |
| Counterimmunoelectrophoresis | - | - | - | Ab/Ag | - | Ab | - |
| Tube precipitin | - | Ab | - | - | - | Ab | - |
| Latex agglutination | - | Ab | Ab | Ab | Ag | Ab | - |
| Lateral flow assay | - | Ab | Ag | - | Ag | Ab | Ag |
| ELISA | Ab/Ag | Ab/Ag | Ab/Ag | Ab/Ag | Ab/Ag | Ab | Ab/Ag |
| Western blot | - | Ab | Ab | Ab/Ag | - | Ab | - |
| Radioimmunoassay | Ab | - | Ag | Ag | - | - | - |
BLM: blastomycosis; CDM: coccidioidomycosis; HPM: histoplasmosis; PCM: paracoccidioidomycosis; CRY: cryptococcosis; SPT: sporotrichosis; TLM: talaromycosis; Ab: antibody; Ag: antigen; ELISA: enzyme-linked immunosorbent assay.