Table 2.

Summary of sensitivity and specificity values of immunological tests used for diagnosis of endemic mycoses by antibody detection.

Disease	Test	Sensitivity	Specificity	References
Histoplasmosis	ID	75–95	100	[58]
	CF	72–95	70–80	[58]
	EIA	66–97	54–100	[65,67,68,69,70]
	Western blot	95	94	[72,73]
Paracoccidioidomycosis	ID	17–100	43.3–100	[99,103,104,110,122]
	EIA	75–100	100	[103,115,116]
	Western blot	77.3–100	73.3–100	[114,118,119,120,123]
	CIE	95–100	100	[99,103,110]
Blastomycosis	ID	28	100	[6]
	CF	9	100	[6]
	EIA	77	92	[6]
Coccidioidomycosis	ID	50–90		[6,44]
	CF	67–75		[6]
	EIA	54–92	97	[6,44]
Sporotrichosis	ID	98	100	[168]
	CIE	98	100	[168]
	EIA	90–100	80–100	[160,161,163,168]
	Western blot	93–100	50–80	[163,170]
Talaromycosis	ID	25	NE	[177,178]
	EIA	13–82	81–100	[179,180]

ID: immunodiffusion; CF: complement fixation; EIA: enzyme immunoassay; CIE: counterimmunoelectrophoresis.